Visualizing Phytochemical-Protein Interaction Networks: and Cancer.

The study of medicinal plants is a rapidly growing field. Techniques such as reverse screening and network pharmacology are used to study the complex cellular action of medicinal plants against disease. However, it is difficult to produce a meaningful visualization of phytochemical-protein interactions (PCPIs) in the cell.

Modelling brain dopamine-serotonin vesicular transport disease in .

Brain dopamine-serotonin vesicular transport disease is a rare disease caused by autosomal recessive mutations in the gene, which encodes the VMAT2 protein. VMAT2 is a membrane protein responsible for vesicular transport of monoamines, and its disruption negatively affects neurotransmission. This results in a severe neurodevelopmental disorder affecting motor skills and development, and causes muscular hypotonia.