Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation.

Background: We aimed to determine the association between seizure termination and side effects of isoflurane for the treatment of refractory status epilepticus (RSE) and super-refractory status epilepticus (SRSE) in neurointensive care units (neuro-ICUs).

Methods: This was a multicenter retrospective study of patients with RSE/SRSE treated with isoflurane for status epilepticus termination admitted to the neuro-ICUs of nine German university centers during 2011-2018.

Results: We identified 45 patients who received isoflurane for the treatment of RSE/SRSE.