Publications by authors named "Alexander Sarachakov"
Article Synopsis
- Follicular lymphoma (FL) is an incurable cancer that arises from B cells in the germinal center and is characterized by genetic changes and a restructured lymphoid microenvironment to evade the immune system.
- The interactions between tumor B cells and their surrounding microenvironment are believed to influence the varying clinical outcomes in FL patients, yet current clinical tools fail to accurately predict these behaviors.
- In a study involving FL patients in a clinical trial, researchers identified specific tumor characteristics and microenvironmental patterns, such as stromal desmoplasia, that are linked to early relapse, indicating potential markers for high-risk patients.
