Publications by authors named "Alexander S Sobolev"
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Synopsis of recent research by authors named "Alexander S Sobolev"
- Alexander S. Sobolev's recent research primarily focuses on the development and application of modular nanotransporters (MNTs) for targeted delivery of therapeutic agents, particularly in the context of oxidative stress, cancer therapy, and viral infections like SARS-CoV-2.
- His studies include the use of MNTs to deliver anti-Keap1 monobodies to inhibit reactive oxygen species in mouse hepatocytes, as well as targeting the degradation of critical viral proteins to suppress SARS-CoV-2 replication.
- Sobolev's work also explores the effective cytoplasmic concentration of bioactive agents interacting with intracellular proteins, with findings suggesting the potential for MNTs to enhance treatment efficacy across various diseases through precise targeting mechanisms.