Publications by authors named "Alexander S Randall"
Article Synopsis
- The study investigated how phosphoinositides interact during phototransduction in Drosophila using fluorescently tagged lipid probes in photoreceptors.
- Tb(R332H) was found to be the best indicator for PtdIns(4,5)P2, while the P4M domain reported PtdIns4P levels.
- The results showed that phosphoinositide depletion in wild-type flies occurs at normal light levels but is significantly higher in mutants without specific channels, suggesting that PLC activity is regulated by Ca(2+) and PKC to maintain phosphoinositide balance.
