Publications by authors named "Alexander R Bennett"
For decades, parasitic worms such as Trichuris muris have been maintained in laboratory animals, providing insights into host-parasite interactions and host immune responses. The most used T. muris isolate is the E isolate, established in the laboratory in 1954.
View Article and Find Full Text PDFMotivation: Structural analysis of glycans poses significant challenges in glycobiology due to their complex sequences. Research questions such as analyzing the sequence content of the α1-6 branch in -glycans, are biologically meaningful yet can be hard to automate.
Results: Here, we introduce a regular expression system, designed for glycans, feature-complete, and closely aligned with regular expression formatting.
Mucin protein glycosylation is important in determining biological properties of mucus gels, which form protective barriers at mucosal surfaces of the body such as the intestine. Ecological factors including: age, sex, and diet can change mucus barrier properties by modulating mucin glycosylation. However, as our understanding stems from controlled laboratory studies in house mice, the combined influence of ecological factors on mucin glycosylation in real-world contexts remains limited.
View Article and Find Full Text PDFArticle Synopsis
- Sexual reproduction in eukaryotes relies on meiosis, which involves crossover events for proper chromosome segregation.
- Elevated temperatures were found to induce an increase in meiotic recombination rates, specifically through the Type I interference sensitive pathway in Arabidopsis thaliana.
- The study suggests that this heat-induced increase in crossovers is unique to thermal stress and provides understanding of how environmental factors influence plant genetic processes, with potential practical implications.