No shortening of the patellar tendon during two-stage total knee arthroplasty revision using articulating spacers.

Background: Surgical techniques in two-stage revision total knee arthroplasty (rTKA) include the use of articulating spacers and static spacers. Shortening of the patellar tendon could be a reason for inferior functional outcomes in two-stage septic rTKA . The aim of this study was to determine if articulating spacers also have negative effects on the extensor mechanism in rTKA.

Impact of intra- and extramedullary alignment on blood loss in total knee arthroplasty: a retrospective study.

Background: There is a scarcity of scientific data regarding the correlation between alignment techniques during total knee arthroplasty (TKA) and blood loss as well as transfusion rates. This study's hypothesis posited that intramedullary-aligned (IM) TKA exhibits higher blood loss and transfusion rates when contrasted with extramedullary-aligned (EM) TKA.

Methods: We conducted a retrospective examination of 883 patients who underwent total knee arthroplasty (TKA) in 2021 at a solitary orthopedic center in Germany.

Pinch Valve Approach for a Biofilm Resistant Mechatronic Intraurethral Artificial Urinary Sphincter.

Stress urinary incontinence is the involuntary leakage of urine during increased abdominal pressure, such as coughing, sneezing, laughing, or exercising. It can have a significant negative impact on a person's quality of life and can result in decreased physical activity and social isolation. The presented closure mechanism for a mechatronic intraurethral artificial urinary sphincter is designed to be inserted minimally invasive into the urethra.

Spontaneous shrinkage drives macromolecule encapsulation into layer-by-layer assembled biopolymer microgels.

Hypothesis: Recently, the anomalous shrinkage of surface-supported hyaluronate/poly-l-lysine (HA/PLL) microgels (µ-gels), which exceeds that reported for any other multilayer-based systems, has been reported [1]. The current study investigates the capability of these unique µ-gels for the encapsulation and retention of macromolecules, and proposes the shrinkage-driven assembly of biopolymer-based µ-gels as a novel tool for one-step surface biofunctionalization.

Experiments: A set of dextrans (DEX) and their charged derivatives - carboxymethyl (CM)-DEX and diethylaminoethyl (DEAE)-DEX - has been utilized to evaluate the effects of macromolecular mass and net charge on µ-gel shrinkage and macromolecule entrapment.

A Novel Concept for Unidirectional Communication With an Active Implant Based on Deliberately Produced Human Body Signals.

A new patient-friendly and discrete approach to build a unidirectional communication path with active implants based on deliberately produced human body signals is presented. The application for which this approach is intended is an artificial urinary sphincter implant, the closure mechanism of which is wirelessly actuated in the event of micturition need. Conventional implant communication methods can be associated with limitations regarding technological implementation and usability, and are used by medical professionals only.

Development of a test bench for the urodynamic simulation of the lower urinary tract.

Stress urinary incontinence restricts the quality of life of affected individuals. To restore continence and increase the quality of life in a long term, the currently applied surgical treatment methods for more severe cases are not sufficient. To support the development of a novel intraurethral artificial sphincter with the goal to replace current systems, a test bench is developed, which simulates the lower urinary tract with regards to its urodynamics.

Electrospun patterned porous scaffolds for the support of ovarian follicles growth: a feasibility study.

Recently, the interest of the scientific community is focused on the application of tissue engineering approach for the fertility restoration. In this paper innovative patterned electrospun fibrous scaffolds were fabricated and used as 3D system for porcine follicles culture. The obtained scaffolds demonstrated to be a suitable support which did not alter or interfere with the typical spherical follicles morphology.