Publications by authors named "Alexander Phu"

Aims: There are limited studies on dipeptidyl-peptidase 4 inhibitor (DPP-4i), sodium glucose cotransporter 2 inhibitor (SGLT2-i), and glucagon-like peptide 1 (GLP-1) receptor agonist use and occurrence of diabetic macular edema (DME). The objective of this study was to determine the association between DPP-4i, SGLT2-i, and GLP-1 receptor agonist use and occurrence of DME.

Methods: Proportional hazard models were used to evaluate the change in hazard of developing DME associated with DPP-4i, SGLT2-i, or GLP-1 receptor agonist use.

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Article Synopsis
  • Quetiapine is an atypical antipsychotic used for various conditions, including schizophrenia, bipolar disorder, and treatment-resistant depression, due to its mood-stabilizing effects.
  • A case report highlights a 42-year-old male who developed psychotic symptoms after starting quetiapine for major depressive disorder, raising concerns about potential quetiapine-induced psychosis.
  • The Naranjo scale assessed the likelihood of an adverse drug reaction, scoring a three, while suggesting other causes for psychosis, emphasizing the need for careful administration and consideration of side effects.
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Serotonin syndrome (SS) describes a life-threatening clinical condition that can develop within hours or days after taking serotonergic medication(s). Medication adverse reactions, overdose, or drug interactions can cause this syndrome. Patients often present with symptoms of hyperthermia, muscle rigidity, hyperreflexia, and clonus.

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