Publications by authors named "Alexander Panaccione"
Article Synopsis
- Two sequencing batch reactors (SBRs) were used to effectively break down toxic munitions DNAN and NTO under both aerobic and anaerobic conditions, with complete removal achieved in anaerobic settings with LB broth.
- The anaerobic SBR showed significant success in biotransformation, reaching 100% removal rates, while the aerobic SBR only managed 58% for DNAN and 45% for NTO, suggesting that anaerobic conditions are more effective for this process.
- Transcriptomic analysis indicated the presence of key genes and bacterial populations involved in the degradation, highlighting potential areas for further research into munitions-degrading organisms and their functional genetics.
Clinical and molecular insights into adenoid cystic carcinoma: Neural crest-like stemness as a target.
Laryngoscope Investig Otolaryngol
August 2016
Objectives: This review surveys trialed therapies and molecular defects in adenoid cystic carcinoma (ACC), with an emphasis on neural crest-like stemness characteristics of newly discovered cancer stem cells (CSCs) and therapies that may target these CSCs.
Data Sources: Articles available on Pubmed or OVID MEDLINE databases and unpublished data.
Review Methods: Systematic review of articles pertaining to ACC and neural crest-like stem cells.
MYC is a transcription factor that is essential for cellular proliferation and development. Deregulation or overexpression of MYC occurs in a variety of human cancers. Ectopic expression of MYC causes hyperproliferation and transformation of cells in culture and tumorigenesis in several transgenic mouse models.
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