Publications by authors named "Alexander Marta"
Article Synopsis
- Pregnancy-associated malaria can lead to negative outcomes, like complications during pregnancy, and is linked to issues with blood flow in the placenta.
- The research found that the TLR4-TRIF-endothelin signaling pathway plays a crucial role in controlling the movement of trophoblasts, which is important for protecting the fetus during infection.
- By studying 401 pregnancies in Brazil and using mouse models, the study revealed that the TLR4 pathway helps regulate the endothelin gene expression in the placenta, thus contributing to fetal protection against malaria.
