Improvement evident but still necessary in clinical practice guideline quality: a systematic review.

Objective: To review the quality of clinical practice guidelines (CPGs) from a wide range of health care topics and report any changes seen since 1992.

Study Design And Setting: A literature search in MEDLINE, EMBASE, Web of Science Core Collection, and BIOSIS was conducted in London, Ontario, Canada. Publications were screened to identify those assessing the quality of CPGs using the Appraisal of Guidelines, Research and Evaluation (AGREE) II instrument.