Does reverse total shoulder arthroplasty for proximal humeral fracture portend poorer outcomes than for elective indications?

Background: The number of reverse total shoulder arthroplasties (RTSAs) performed annually has increased, and the indications for RTSA have expanded beyond rotator cuff arthropathy to include treatment of complex proximal humeral fractures. No studies exist comparing clinical, functional, and radiographic outcomes in patients receiving RTSA for the treatment of acute fracture vs. those undergoing the procedure for degenerative conditions.

Set it and Forget it: Diaphyseal Fractures of the Humerus Undergo Minimal Change in Angulation After Functional Brace Application.

Objectives: To quantify radiographic changes observed in humeral shaft frctures throughout course of treatment with functional bracing.

Design: Retrospective cohort study.

Setting: Level 1 Trauma Center and affiliated Tertiary Care Center.

Functional Outcomes of Compression Plating and Bone Grafting for Operative Treatment of Nonunions About the Forearm.

Purpose: To describe one center's experience with nonunion of one or both bones of the forearm and report on the functional recovery of patients treated for a single- or 2-bone forearm nonunion.

Methods: We performed a retrospective analysis of 23 patients who presented to our institution over an 11-year period and underwent surgical repair of a forearm nonunion (radius, ulna, or both bones). The main outcome measurements included time to union, visual analog scale pain scores, range of motion, Short Musculoskeletal Function Assessment scores, and postoperative complications.

Posttraumatic Malalignment of the Humeral Shaft: Challenging the Existing Paradigm.

Objective: To investigate the impact of posttraumatic humeral shaft malalignment on the ability to position the hand in space.

Methods: Two unique models were created: a cadaveric model and a computerized 3-dimensional (3D) model. In the cadaveric model, a midshaft transverse osteotomy of the humerus was created to simulate fracture.

Development of Compartment Syndrome Negatively Impacts Length of Stay and Cost After Tibia Fracture.

Objectives: To quantify the impact of compartment syndrome in the setting of tibial shaft fracture on hospital length of stay (LOS) and total hospital charges.

Design: Retrospective case-control study.

Setting: All New York State hospital admissions from 2001 to 2011, as recorded by the New York Statewide Planning and Research Cooperative System database.

Murine mammary carcinoma cells and CD11c(+) dendritic cells elicit distinct responses to lipopolysaccharide and exhibit differential expression of genes required for TLR4 signaling.

Although TLR are often studied on DC because of their ability to bridge innate and adaptive defenses, TLR are also expressed by epithelial cells. Because the majority of cancers are carcinomas, and thus of epithelial origin, we wanted to know whether a carcinoma and DC responded similarly to a TLR agonist. We found the mammary carcinoma 4T1 and CD11c(+) DC both secreted proinflammatory chemokines in response to the TLR4 agonist lipopolysaccharide (LPS).