Publications by authors named "Alexander Loh"

Article Synopsis
  • Tyrosine kinase inhibitors (TKIs), especially ibrutinib, are commonly used to treat blood cancers, but there are concerns about arrhythmias associated with these medications.
  • A study analyzed 193 patients on long-term cardiac monitoring, revealing that those on ibrutinib had a significantly higher occurrence of atrial fibrillation and non-sustained ventricular tachycardia compared to those on other TKIs or non-TKI treatments.
  • The findings suggest that 25% of ibrutinib patients had to pause their treatment due to arrhythmias, highlighting the need for careful heart monitoring in patients receiving this type of therapy.
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Purpose: To describe the technique and document utility of adjunctive cone-beam CT (CBCT) in patients undergoing bronchial artery embolization (BAE) or chemoinfusion (BAC).

Materials And Methods: Between August 2010 and February 2021, 26 patients (62 bronchial arteries) were evaluated with CBCT in addition to the usual digital subtraction angiography (DSA) during BAE or BAC. 19 patients (43 arteries) underwent BAE for hemoptysis; 7 patients (19 arteries) had BAC for palliation of lung malignancy.

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Lymph leaks after vascular groin dissections can be a challenging postoperative complication for both patient and surgeon. A multidisciplinary team at a district general hospital in the United Kingdom consisting of breast, plastic, and vascular surgeons performed intraoperative lymphatic mapping using patent blue V dye to locate the exact location of a groin lymph leak before sealing the leak with direct vision ligation and Floseal Hemostatic Matrix (Baxter Healthcare Corp., Hayward, CA).

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Acute upper limb ischaemia (AULI) can be managed surgically, via interventional radiology, and conservatively, but no real guidelines exist for when a conservative approach is appropriate. A systematic review of the literature is presented of the surgical, radiological and conservative management of AULI. A search was performed using the electronic databases Medline and Embase.

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Article Synopsis
  • - A 30-year-old man with type I neurofibromatosis underwent an above-knee amputation due to complications like bleeding, infection, swelling, and severe joint instability.
  • - After the surgery, he experienced ongoing bleeding from the amputation site.
  • - Angiography showed multiple small aneurysms causing the bleeding, and doctors successfully stopped the bleeding using microcoil embolization.
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Diabetic foot ulcers are a source of significant morbidity. Maximizing limb salvage is an important long-term objective. The use of dermal substitutes to aid limb salvage and reduce amputation rates has been described recently in the literature.

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