Calcium hydroxylapatite filler for facial rejuvenation: a histologic and immunohistochemical analysis.

BACKGROUND Soft-tissue augmentation using calcium hydroxylapatite (CaHA) filler has been shown to be a safe and effective filler agent. A previous study utilizing electron microscopy demonstrated deposition of collagen around filler microspheres with minimal inflammatory response. OBJECTIVE The purpose of this study was to further characterize the expression of collagen in response to injected CaHA filler material using conventional, special, and immunohistochemical (IHC) staining.

Evaluation of clinical, microscopic, and ultrastructural changes after treatment with a novel Q-switched Nd:YAG laser.

Background: The Q-switched Nd:YAG laser was among the first non-ablative lasers to be used. High-fluence photoacoustic Q-switched laser treatments were shown to produce results akin to those seen with some ablative lasers. Previous low-fluence, non-thermal, Q-switched Nd:YAG lasers produced almost no results.

Histologic and ultrastructural analysis of melasma after fractional resurfacing.

Background And Objective: Fractional photothermolysis is a popular treatment option for photodamaged skin and other cutaneous conditions. Recently, successful improvement in melasma has been achieved with this laser system. We undertook this study to evaluate the ultrastructural changes associated with fractional laser treatment of melasma.

Clinical, laboratory, and MRI analysis of cellulite treatment with a unipolar radiofrequency device.

Background: Cellulite is seen in more than 85% of postpubertal women. Recent studies show that bipolar radiofrequency and low-level laser devices can produce mild skin tightening of cellulite.

Objective: The primary objective was to determine if a novel unipolar, more deeply penetrating, radiofrequency device can promote better skin tightening with fewer treatments than is seen with previously described devices.

Treatment of photoaging with a very superficial Er:YAG laser in combination with a broadband light source.

Background And Objective: Studies documenting improvement following combined laser and light-based devices are needed. The objective of this study was to evaluate clinical, histological, and ultrastructural changes in photodamaged facial skin following sequential treatment with ablative superficial erbium:YAG (Er:YAG) laser peels and nonablative intense pulsed light, or broadband light (BBL), treatments.

Study Design/materials And Methods: Fifteen subjects with photodamaged facial skin and Fitzpatrick skin types I to III underwent 3 monthly treatments with the Profile system (Sciton, Inc, Palo Alto, CA) utilizing very superficial MicroLaserPeel settings of 2.

Cutaneous photoaging treated with a combined 595/1064 nm laser.

Background And Objectives: The pulsed dye laser (PDL) has been used for a variety of vascular changes associated with photoaging. The Nd:YAG laser has been shown to be effective in the treatment of deeper facial vessels, as well as to stimulate new dermal collagen deposition. This study was undertaken to evaluate the safety and efficacy of sequential dual-wavelength PDL and Nd:YAG laser treatment of photoaged facial skin.

Treatment of skin laxity of the lower face and neck in older individuals with a broad-spectrum infrared light device.

Background: Non-ablative approaches with infrared and radiofrequency energy sources have been shown to reduce skin laxity, but studies have focused on individuals with early-stage, mild-to-moderate degenerative dermal changes.

Objective: The purpose of this prospective study was to evaluate the safety and efficacy of an infrared light device for the treatment of skin laxity in patients with soft tissue ptosis of the lower face and neck characteristic of the sixth decade of life and beyond.

Materials And Methods: Thirteen females, aged 58-83 years old (average: 64 years), were treated with a filtered 1100-1800 nm infrared light-based device.

Coexistence of erythromelalgia and Raynaud's phenomenon.

Erythromelalgia is characterized by spontaneous recurrent episodes of redness, heat, and pain of the extremities that can be triggered or worsened by heat. Raynaud's phenomenon occurs in response to cold exposure and presents as pallor of the fingers or toes, often followed by cyanosis and rubor. Although the 2 conditions may appear to be opposites in symptomatology and clinical presentation, there are very rare reports of their coexistence.

Hiccups, eructation, and other uncommon prodromal manifestations of herpes zoster.

Although the most frequent presentation of herpes zoster involves sensory neurons, motor and autonomic symptomatology is also known to occur in this disease. An unusual symptom of hiccups is described here. Other infrequent manifestations of this common illness, including the Ramsay Hunt syndrome, herpes zoster ophthalmicus, urinary and fecal retention, sexual dysfunction, and zoster sine herpete, are reviewed.

Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology.

Unlabelled: Incontinentia pigmenti is an uncommon X-linked dominant disorder, lethal in the majority of affected males in utero and variably expressed in females. Cutaneous manifestations are classically subdivided into 4 stages: vesicular, verrucous, hyperpigmented, and atrophic. Various hair and nail abnormalities, dental anomalies, and ophthalmologic and neurologic deficits are associated with the disorder.

Use of CO2 laser in the treatment of periungual fibromas associated with tuberous sclerosis.

Background: Tuberous sclerosis complex is an autosomal dominant disorder with variable clinical expression. In severe forms it may involve almost any organ system. Periungual fibromas are a common cutaneous manifestation and a frequent source of cosmetic and functional concern.