Impact of pesticide formulation excipients and employed analytical approach on relative matrix effects of pesticide determination in strawberries.

Relative matrix effects between an ambient mass spectrometric technique known as coated blade spray (CBS) and liquid chromatographic separation approach when applied to multiresidue pesticide analysis in strawberry samples are explored. Acceptable slope relative standard deviations (RSD <15 %) were observed for the 9 compounds under study for both CBS-MS/MS (2.2-12.

Multi-class pesticide analysis in cannabis oil using coated blade spray and solid-phase microextraction with liquid chromatography coupled to mass spectrometry.

The application of solid-phase microextraction (SPME) coupled to mass spectrometry to provide a high-throughput and cost-effective solution to multi-residue analysis of pesticides in cannabis oil samples has not been extensively explored. In this work, the method development steps for the extraction of an initial target list of 74 pesticides from cannabis oil via SPME for analysis with both LC-MS/MS and coated blade spray (CBS) are presented. The exploration of a washing step to remove adhered oil whilst minimally desorbing extracted analytes along with the implementation of central composited design investigation to examine compound extraction kinetics in the non-polar matrix yielded a workflow that was validated via both instrumental techniques.

Multiresidue pesticide quantitation in multiple fruit matrices via automated coated blade spray and liquid chromatography coupled to triple quadrupole mass spectrometry.

Application of ambient mass spectrometry techniques to accelerate analysis of pesticides in produce, with technique validation via chromatographic separation, has not been explored extensively. In this work, coated blade spray (CBS) was used to provide freedom of instrumental choice for a multiresidue panel of pesticides in apple, blueberry, grape, and strawberry through direct-coupling with mass spectrometry (MS) and liquid chromatographic (LC) analyses. For all four matrices, >125 compounds were found to meet European Union guidelines concerning linearity, precision, and accuracy while both CBS-MS/MS and SPME-LC-MS/MS methods achieved limits of quantitation below their minimum regulatory limits.

Breaching the 10 Second Barrier of Total Analysis Time for Complex Matrices via Automated Coated Blade Spray.

In the development of modern analytical workflows, parameters such as sample turnaround time, cost of analysis, and ease of use must be prioritized. Automation enables reductions in total analysis time, human intervention, and cost per sample. In this report, a suitable automated coated blade spray (CBS) workflow is proposed for the screening and quantitation of multiple substances (i.