A prevalence study in Guadalajara, Mexico, comparing tuberculin skin test and QuantiFERON-TB Gold In-Tube.

Background: Tuberculosis (TB) is a prevalent disease throughout the world. The extent of TB illness in childhood is not clear; recent data shows that 10-20% of the cases are found in children under 15 years old. In 2017, 1 million children developed the disease, of which 9% were co-infected with HIV.

Molecular epidemiology of tuberculosis in Havana, Cuba, 2009.

Objectives: To estimate the proportion of tuberculosis cases attributable to recent transmission and the risk factors possibly associated with tuberculosis clustering.

Methods: Population-based study combining information from epidemiological investigation of tuberculosis cases notified to the National Tuberculosis Control Program in Havana, Cuba, in 2009 with the results of genotyping of Mycobacterium tuberculosis isolates with variable number tandem repeat of mycobacterial interspersed repetitive units (MIRU-VNTR) typing.

Results: Of 186 cases, 61 were genotyped: 33 patterns and five clusters with 19, 7, 3, 2 and 2 cases were found.

[Trends and predictions of tuberculosis, and challenges towards tuberculosis eradication in Havana City].

Objectives: To describe the variation and the trend of new tuberculosis case reports in Havana from 1995 to 2010, as well as their projection and occurrence for 2011-2013.

Methods: A time series study was conducted, and the annual total and mean variation percentages of rates by clinical and bacteriological categories, age, municipal distribution and TB/HIV co-infection were analyzed. Estimation of projections by using two-parameter exponential smoothing techniques was made.

[Tuberculosis incidence strata in Cuban municipalities: 1999-2002 and 2003-2006].

Objective: identify Cuban municipalities with high, medium, and low incidence of tuberculosis (TB), compare incidence rates for the periods 1999-2002 and 2003-2006, and analyze distribution of the disease by population density and economic activity.

Methods: TB incidence was calculated by municipality, confidence interval (95%), and the percentage of variation for the defined strata according to population density and the predominant economic activity. The municipalities were divided into three categories based on incidence (> 10 per 100 000; > 5 per 100 000 to < 10 per 100 000, and < 5 per 100 000), and maps were plotted.