Routine data sharing, defined here as the publication of the primary data and any supporting materials required to interpret the data acquired as part of a research study, is still in its infancy in psychology, as in many domains. Nevertheless, with increased scrutiny on reproducibility and more funder mandates requiring sharing of data, the issues surrounding data sharing are moving beyond whether data sharing is a benefit or a bane to science, to what data should be shared and how. Here, we present an overview of these issues, specifically focusing on the sharing of so-called "long tail" data, that is, data generated by individual laboratories as part of largely hypothesis-driven research.
View Article and Find Full Text PDFBackground: Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of the major bottlenecks in developing bio-ontologies is the lack of a unified methodology. Different methodologies have been proposed for different scenarios, but there is no agreed-upon standard methodology for building ontologies.
View Article and Find Full Text PDFIntegrating information in the molecular biosciences involves more than the cross-referencing of sequences or structures. Experimental protocols, results of computational analyses, annotations and links to relevant literature form integral parts of this information, and impart meaning to sequence or structure. In this review, we examine some existing approaches to integrating information in the molecular biosciences.
View Article and Find Full Text PDFBackground: Computational methods for problem solving need to interleave information access and algorithm execution in a problem-specific workflow. The structures of these workflows are defined by a scaffold of syntactic, semantic and algebraic objects capable of representing them. Despite the proliferation of GUIs (Graphic User Interfaces) in bioinformatics, only some of them provide workflow capabilities; surprisingly, no meta-analysis of workflow operators and components in bioinformatics has been reported.
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