Coexistence an aberrant right subclavian artery with other congenital anomalies: case report and review of the literature.

Aberrant right subclavian artery is the most common aortic arch anomaly that frequently occurs in coexistence with other congenital cardiovascular anomalies. A 32-year-old male patient was hospitalized with ventricular septal defect, chronic heart failure NYHA class III, pulmonary arterial hypertension. Contrast-enhanced multislice computed tomography revealed membranous ventricular septal defect, persistent left superior vena cava, bicuspid aortic valve and aberrant right subclavian artery.

Combined low-frequency ultrasound and streptokinase intravascular destruction of arterial thrombi in vivo.

To prevent a distal embolization in the course of ultrasound (US) angioplasty, we combined US thrombus disruption in peripheral artery in vivo with simultaneous administration of streptokinase (SK). Acute thrombosis was induced in the femoral arteries of 23 dogs. Two hours after thrombus formation, thrombus destruction was performed using US (36 kHz) and by a combined US+SK (75,000 U/kg) administration.

Method for disruption and re-canalization of atherosclerotic plaques in coronary vessels with photothermal bubbles generated around gold nanoparticles.

Background And Objectives: Rapid and safe re-canalization of totally occluded coronary vessels, especially those with the calcified plaques, represent a challenge for cardiology.

Study Design/materials And Methods: We have suggested to employ photothermal microbubbles (PTMBs) that are generated around injected to plaque or thrombus gold nanoparticles with a short laser pulse for selective mechanical disruption and removal of the plaque tissue and without thermal and mechanical damage to arterial wall. PTMBs were generated in vitro around 30-250 nm gold spheres and with 10 nanoseconds laser pulse at 532 nm in three models: the layer of the living fibroblasts, the epoxy layers, and human arteries with plaques.