The mechanoresponse of bone is closely related to the osteocyte lacunocanalicular network architecture.

Organisms rely on mechanosensing mechanisms to adapt to changes in their mechanical environment. Fluid-filled network structures not only ensure efficient transport but can also be employed for mechanosensation. The lacunocanalicular network (LCN) is a fluid-filled network structure, which pervades our bones and accommodates a cell network of osteocytes.

Experimental investigation of the effect of surface roughness on bone-cement-implant shear bond strength.

Debonding of cemented bone implants is regarded as a major contributor to complications. The relationship between shear bond strength and surface roughness has been investigated, however there are inconsistencies in the trends reported in different studies. The shear strength between poly(methyl methacrylate) bone-cement and sand blasted cobalt-chromium and titanium alloy surfaces was measured to investigate the relationship between interfacial shear strength and surface topology.