Publications by authors named "Alexander Ethell"
Article Synopsis
- - The study investigates mitotically stable random monoallelic gene expression (RME) in certain autosomal genes, focusing on the role of enhancers in this process using a mouse model and single-cell analysis of NK cell receptor genes.
- - Findings show that enhancers can be accessible and active in both silent and expressed alleles, indicating that enhancer activation and gene expression can operate independently.
- - The research suggests that many genes may exhibit RME as a result of general enhancer-driven gene regulation, challenging the idea that certain lineage-defining genes are universally expressed and positioning RME as part of a broader continuum of gene regulation behaviors.
