Publications by authors named "Alexander E Guschin"
Article Synopsis
- LGV (lymphogranuloma venereum) has been found prevalent among men who have sex with men (MSM) in Moscow for the first time, with a significant percentage (68.8%) of those with rectal chlamydia (CT) also testing positive for LGV.
- Factors such as older age and group-sex practices were linked to a higher incidence of LGV, including a strong correlation with HIV-positive status among those infected.
- Diagnosis of LGV can be complicated due to similar symptoms with inflammatory bowel disease, highlighting the necessity for targeted laboratory testing for LGV in MSM, which is currently insufficient in Russia.
Objective: The aim of the study was to evaluate the diagnostic value of Nugent score, wet mount microscopy, and polymerase chain reaction (PCR) test developed in Russia for bacterial vaginosis (BV) diagnosis.
Materials And Methods: One hundred Caucasian women were enrolled in this study. Three vaginal samples were taken from each participant: 1 for PCR analysis, 1 for Nugent score evaluation, and 1 for wet mount microscopy.
The frequency ADH2-2 allele in the Moscow urban population and a correlation between the ADH2-2 allele, alcoholic dependence without cirrhosis, symptomatic alcoholic cirrhosis and status on hepatitis B and C infection have been studied. One hundred and twenty-three inhabitants of Moscow (50 healthy donors, 36 patients with alcoholic cirrhosis (subdivided into infected and uninfected by HBV and/or HCV) and 37 patients with alcoholic dependence) of a similar age/sex and drinking pattern have been analysed. The frequency of 41% for ADH2-2 allele is characteristic for an urban Moscow population.
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