Publications by authors named "Alexander D Shitikov"
Article Synopsis
- Some animals like fish and frogs can grow back parts of their bodies, but reptiles, birds, and mammals (amniotes) can't do this as well.
- Scientists think that changes like better immune systems, tough skin, warm blood, and bigger body sizes made it harder for amniotes to regrow parts.
- The loss of special genes that help with regrowth happened later, which might mean that evolution took time to adjust how animals develop as these changes happened.
Background: It is generally accepted that most evolutionary transformations at the phenotype level are associated either with rearrangements of genomic regulatory elements, which control the activity of gene networks, or with changes in the amino acid contents of proteins. Recently, evidence has accumulated that significant evolutionary transformations could also be associated with the loss/emergence of whole genes. The targeted identification of such genes is a challenging problem for both bioinformatics and evo-devo research.
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