Publications by authors named "Alexander DʼAmour"

Article Synopsis
  • * The approach uses shared assumptions about confounding to simplify and strengthen sensitivity analyses, allowing for stronger causal conclusions.
  • * We apply this method to both simulated data and real data from the National Health and Nutrition Examination Survey (NHANES) to demonstrate how it can help quantify the reliability of causal effect estimates.
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Advances in machine learning for health care have brought concerns about bias from the research community; specifically, the introduction, perpetuation, or exacerbation of care disparities. Reinforcing these concerns is the finding that medical images often reveal signals about sensitive attributes in ways that are hard to pinpoint by both algorithms and people. This finding raises a question about how to best design general purpose pretrained embeddings (GPPEs, defined as embeddings meant to support a broad array of use cases) for building downstream models that are free from particular types of bias.

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Accurate measurement of daily infection incidence is crucial to epidemic response. However, delays in symptom onset, testing, and reporting obscure the dynamics of transmission, necessitating methods to remove the effects of stochastic delays from observed data. Existing estimators can be sensitive to model misspecification and censored observations; many analysts have instead used methods that exhibit strong bias.

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Article Synopsis
  • There are over 90 serotypes of Streptococcus pneumoniae, and previous studies suggest that being a carrier can help reduce colonization time in a way that is not specific to any one serotype.
  • Researchers conducted a study on Kenyan children aged 3-59 months to track how long different serotypes were carried, finding that 66% of initial swabs were positive for pneumococcus.
  • The study revealed varying rates of acquisition and clearance among serotypes, with some more resistant to competition and a general decline in carriage duration as children age, which could inform future vaccine effectiveness studies.
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