Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses ().

The pharmacokinetics and tolerability of cannabinoids and their metabolites were determined in eight horses after enteral administration of a commercial CBD/CBDA-rich hemp oil product. Each horse was administered 2 mg/kg or 8 mg/kg CBD/CBDA or no treatment in a randomized cross-over design. Serial serum samples collected over 48 h were analyzed by high performance liquid chromatography with tandem mass spectrometry.

Current Concepts in Head and Neck Surgery.

This article is intended to "brush up" on the literature updates for the management of head and neck surgeries, particularly mandibulectomy and maxillectomy. Few new techniques have been described in the past decade in dental and oral oncological surgery. A tendency of developing more aggressive surgical strategies to treat complex oral tumors is evident from the recent veterinary literature and the emerging novel techniques for bone regeneration of maxillofacial defects.

Evaluation of the effect of ultrasound guidance on the accuracy of intercostal nerve injection: a canine cadaveric study.

Objective: To develop an ultrasound-guided approach to intercostal nerve injection and to compare the success rate of intercostal nerve injections using blind or ultrasound-guided technique in canine cadavers.

Study Design: Prospective, randomized, descriptive, experimental anatomic study.

Animals: A total of 14 mid-sized adult canine cadavers.