Publications by authors named "Alexander Blanchette"
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Synopsis of recent research by authors named "Alexander Blanchette"
- Alexander Blanchette's recent research primarily focuses on assessing the health risks associated with various environmental exposures, including the risks posed by electric arc furnace (EAF) slag and the genotoxic potential of smoke flavoring products, utilizing advanced modeling approaches such as Bayesian methods and physiologically based pharmacokinetic (PBPK) modeling.
- His studies highlight significant findings on the bioavailability of manganese from EAF slag, emphasizing the influence of high iron content on oral bioavailability, and he has contributed to understanding the cardiotoxicity of chemicals through human induced pluripotent stem cell (iPSC)-derived cardiomyocytes.
- Blanchette's work also addresses the need for health-based inhalation guidelines for manganese, the development of toxic equivalency factors for dioxins, and innovative strategies for population-based in vitro testing to evaluate chemical hazards, underscoring the importance of incorporating population variability in toxicological assessments.
