Publications by authors named "Alexander Alliluev"
Article Synopsis
- * Various diagnostic methods exist to detect TB biomarkers like DNA, proteins, and antibodies using techniques such as PCR, ELISA, and flow cytometry, which help identify infections through optical signals.
- * Recent advancements in biosensing focus on enhancing detection sensitivity using fluorescent quantum dots, which offer brighter and more stable optical tags for identifying TB biomarkers more effectively.
Immunization of mice with recombinant IgA1 protease of Neisseria meningitidis or several structural derivatives thereof protects the animals infected with a variety of deadly pathogens, including N. meningitidis serogroups A, B, and C and 3 serotypes of Streptococcus pneumonia. In sera of rabbits immunized with inactivated pneumococcal cultures, antibodies binding IgA1-protease from N.
View Article and Find Full Text PDFObjectives: A new approach to estimation of IgA subclass levels and IgA1/IgA2 ratio using enzymatically active and inactive forms of Neisseria meningitidis IgA1 protease was developed.
Results: The approach was tested using the sera of healthy volunteers and patients with meningococcal meningitis. There was a significant increase in the IgA1 level in patients with meningitis (mean titer 1:1546 ± 352) compared to healthy volunteers (mean titer 1:546 ± 282), while the IgA2 content remained unchanged.