Publications by authors named "Alexander A Bessudnov"
Mol Ecol Resour
April 2022
Article Synopsis
- DNA hybridization-capture techniques help researchers focus on specific genomic regions, which is particularly beneficial for studying ancient DNA (aDNA) that often contains more environmental DNA than the target material.
- hyRAD is introduced as a budget-friendly, design-free method that uses double enzymatic restriction to create RNA probes for capturing targeted regions in aDNA, yielding impressive results from samples with low endogenous content.
- The study highlights the effectiveness of hyRAD, noting that it can enhance data quality and coverage, and has developed an automated protocol to streamline processing, making it a viable option for reconstructing ancestral genetic data.
