Drugs Real World Outcomes
September 2024
Background: Digoxin is a widely prescribed drug for congestive heart failure and atrial fibrillation. Digoxin has a narrow therapeutic index and toxicity can develop quite easily. Digoxin immune fab (DIF) is an effective treatment for toxicity, however there are limited studies characterizing its impact on clinical outcomes in real-world clinical practice.
View Article and Find Full Text PDFBackground: The American College of Surgeons and state regulations mandate that trauma facilities offer trauma-specific continuing education throughout the region they serve. These requirements come with unique challenges when serving a rural and sparsely populated state. A novel approach to providing education was necessitated by the coronavirus disease 2019 pandemic, travel distance, and limited local specialists.
View Article and Find Full Text PDFBackground: Although existing trauma nurse courses provide basic education, advanced courses with simulation experiences that enhance team leadership, communication, and workflows are lacking.
Objective: To design and implement the Advanced Trauma Team Application Course (ATTAC) to promote advanced skills for nurses and respiratory therapists with varied experience and skill levels.
Methods: Trauma nurses and respiratory therapists were selected to participate based on years of experience and the novice to expert nurse model.
Background: Anaphylaxis is a systemic allergic reaction that is commonly treated in the emergency department (ED). The risk of a biphasic reaction is the rationale for observation.
Objective: To derive a prediction rule to stratify ED anaphylaxis patients at risk of a biphasic reaction.
The photodegradation rate of the herbicide imazethapyr on epicuticular waxes of soybean and corn plants was investigated. Plant age, relative humidity, temperature, and number of light banks were varied during plant growth, analyzed statistically, and examined to determine if these factors had an effect on the photodegradation of imazethapyr. Through ultraviolet/visible (UV-Vis) and fluorescence spectroscopy, epicuticular wax characteristics of soybean and corn plants were explored, were used to confirm observations determined statistically, and explain correlations between the rate constants and the composition of the epicuticular waxes.
View Article and Find Full Text PDFThe photodegradation of the imidazolinone herbicides imazamox, imazapic, imazaquin, and imazamethabenz-methyl has been investigated in phosphate-buffered solutions and buffered solutions containing natural organic matter (NOM). The hydrolysis of imazamethabenz-methyl, the only imidazolinone herbicide susceptible to hydrolysis, was also examined. The rate of hydrolysis of imazamethabenz-methyl increased with increasing pH, with the para isomer degrading more rapidly than the meta isomer.
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