Publications by authors named "Alexa Israeli"

Article Synopsis
  • A survey revealed that SPF is the top priority for patients when choosing sunscreen, but preferences differ based on whether they are in urban or rural areas.
  • There may be a lack of awareness about sunscreen recommendations among patients, indicating a need for better educational programs.
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This report presents two cases of patients with long-standing, treatment-resistant Hailey-Hailey disease (HHD) who experienced significant symptom relief through a combination therapy of oral naltrexone and dupilumab injections. The therapeutic potential of targeting the Th2 pathway and Ca signaling with dupilumab in managing HHD manifestations is highlighted. The findings suggest that Th2 blockade with dupilumab, in conjunction with naltrexone, effectively controls recalcitrant HHD, indicating a role of cytokine response in altering disease pathogenesis.

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Article Synopsis
  • Acne fulminans (AF) is a rare and severe skin disorder that causes painful nodules and ulcers, primarily affecting adolescent males with a history of acne.
  • * The condition is often associated with isotretinoin therapy and high testosterone levels, but its exact cause is unknown. Standard treatments include corticosteroids and isotretinoin.
  • * In a reported case, a 17-year-old male with AF did not respond to these treatments but improved significantly when treated with ustekinumab, allowing for a reduction in corticosteroids and an increase in isotretinoin dosage.*
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Caffeine is ubiquitous in our society-not only in the drinks consumed but also increasingly in dermatologic topicals. Given that coffee and caffeine are increasingly used for the production of many dermatologic anti-cancer topicals, sunscreens, and cosmetics, it is of imperative importance to review the basic science and clinical evidence for such claims. In this concise review, we outline the current evidence.

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