Publications by authors named "Alexa Conomikes"
Age-related macular degeneration (AMD) is one of the leading causes of vision loss in the elderly. This disease involves oxidative stress burden in the retina leading to death of retinal pigment epithelial (RPE) cells and photoreceptors. The retina is susceptible to oxidative stress, in part due to high metabolic activity and high concentration of polyunsaturated fatty acids that undergo lipid peroxidation chain reactions.
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- Risk stratification can help identify patients in primary care who are at higher risk of developing melanoma.
- A validated risk stratification tool was converted into a tablet-based questionnaire, which was completed by patients before their primary care visits from 2019 to 2021.
- Out of nearly 8,000 respondents, 26% were classified as high-risk, and the study found that a screening of 64 patients was needed to identify one case of melanoma among that group, highlighting the effectiveness of such tools in targeted screening.