Synopsis of recent research by authors named "Alex Vielma"
- Alex Vielma's recent research primarily focuses on the interactions and signaling mechanisms of neurotransmitters and receptors in retinal cells, with significant emphasis on cannabinoid and purinergic signaling pathways impacting visual processing and exocytosis in chromaffin cells.
- Key findings indicate that activation of type 1 cannabinoid receptors (CB1Rs) in the retina reduces glutamate release and alters inhibitory feedback to bipolar cells, while purinergic receptors (P2X7) contribute to catecholamine secretion in endocrine cells through autocrine signaling.
- Vielma's studies highlight critical physiological effects of high glucose conditions on retinal function, exploring how diabetes influences early neuronal damage, suggesting potential avenues for biomarkers in diabetic retinopathy.
