Publications by authors named "Alex Vaccaro"

Article Synopsis
  • The paper discusses the importance of structured guidelines for returning to activity after spinal deformity surgery, emphasizing that a consistent approach can improve patient recovery and health outcomes.
  • It categorizes diverse patient groups, including early onset scoliosis, adolescent idiopathic scoliosis, young adults, adult spinal deformity, elite athletes, and general sports participants, offering tailored recommendations for each.
  • The document stems from an educational webinar and aims to standardize postoperative protocols, enhancing both surgeon practice and overall patient care.
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Article Synopsis
  • The study evaluated the reliability of the AO Spine-DGOU Osteoporotic Fracture classification system using a cross-sectional survey with 23 trauma experts rating 33 cases at two different times.
  • The calculated kappa statistics indicated moderate inter-rater agreement and substantial intra-rater reproducibility, suggesting that while raters differed slightly, individual consistency was high.
  • The findings highlight the importance of training in improving the reliability of the classification system for identifying fracture patterns and guiding treatment.
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Background: The anatomic interplay and overlap between the cervical spine and the shoulder constitutes a challenge for shoulder and spine surgeons, as symptoms of spine and shoulder pathologies are often similar and may lead to entity misdiagnosis.

Methods: PubMed, Cochrane, and Google Scholar (page 1-20) searches were updated to October 2023 in search of the qualified papers. Boolean Operators were used with a combination of the keywords "spine" OR "neck" And "Shoulder".

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Article Synopsis
  • This study reviews literature to identify factors that influence sexual and partnership adjustment for individuals with spinal cord injuries.
  • The research followed a scoping review framework, analyzing relevant studies from databases like Medline and Scopus, with no limits on publication date or methodology.
  • Findings reveal that sexual health in individuals with spinal cord injuries is influenced by numerous factors, including anatomy, injury level, psychological and social factors, economic status, and relationship type, with implications for improving clinical care and quality of life.
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Purpose: This study aimed to implement the Quality of Care (QoC) Assessment Tool from the National Spinal Cord/Column Injury Registry of Iran (NSCIR-IR) to map the current state of in-hospital QoC of individuals with Traumatic Spinal Column and Cord Injuries (TSCCI).

Methods: The QoC Assessment Tool, developed from a scoping review of the literature, was implemented in NSCIR-IR. We collected the required data from two primary sources.

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Study Design: Survey of cases.

Objective: To evaluate the opinion of experts in the diagnostic process of clinically relevant Spinal Post-traumatic Deformity (SPTD).

Summary Of Background Data: SPTD is a potential complication of spine trauma that can cause decreased function and quality of life impairment.

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Study Design: Survey among spine experts.

Objective: To investigate the different views and opinions of clinically relevant spinal post-traumatic deformity (SPTD).

Summary Of Background Data: There is no clear definition of clinically relevant SPTD.

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Study Design: Scoping review.

Objectives: To describe the meaning of cognitive appraisals, their relation with outcome. measures, and adapted appraisal scales after Spinal Cord Injury (SCI) in the existing literature.

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Study Design: Systematic review: Considering the infiltrative nature of intramedullary astrocytoma, the goal of surgery is to have a better patient related outcome.

Objective: To compare the overall survival (OS) and neurologic outcomes of complete vs incomplete surgical resection for patients with intramedullary astrocytoma.

Methods: A comprehensive search of MEDLINE, CENTRAL and EMBASE was conducted by two independent reviewers.

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Study Design: This was a retrospective cohort study.

Objective: The objective of this study was to determine if the degree of interbody cage lordosis and cage positioning are associated with changes in postoperative sagittal alignment after single-level transforaminal lumbar interbody fusion (TLIF).

Summary Of Background Data: Ideal sagittal alignment and lumbopelvic alignment have been shown to correlate with postoperative clinical outcomes.

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Purpose: To gain insight into current research regarding prehospital care (PHC) in patients with potential traumatic spinal cord injury (TSCI) and to disseminate the findings to the research community.

Methods: In March 2019, we performed a literature search of publications from January 1990 to March 2019 indexed in PubMed, gray literature including professional websites; and reference sections of selected articles for other relevant literature. This review was performed according to Arksey and O'Malley's framework.

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Background: Numerous preclinical studies have been performed in recent years on the effects of the administration of growth factor gene-modified cells in spinal cord injury (SCI). However, findings of these studies are contradictory.

Objective: The present study aims to conduct a systematic review and meta-analysis of animal studies evaluating the effects of administration of growth factor gene-modified cells on locomotion recovery after SCI.

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Study Design: Retrospective review of 2532 adults who underwent elective surgery for cervical radiculopathy or myelopathy with intraoperative neuromonitoring (IONM) with motor evoked potentials (MEPs) between 2017 and 2019.

Objective: Evaluate attainability of monitorable MEPs across demographic, health history, and patient-reported outcomes measure (PROM) factors.

Summary Of Background Data: When baseline IONM responses cannot be obtained, the value of IONM on mitigating the risk of postoperative deficits is marginalized and a clinical decision to proceed must be made based, in part, on the differential diagnosis of the unmonitorable MEPs.

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The threshold for statistical significance is determined by the maximum allowable probability of Type I error (α). For studies that test multiple hypotheses or make multiple comparisons, the probability of at least 1 Type I error (family-wise error rate; FWER) increases as the number of hypotheses/comparisons increase. It is generally best practice to set the acceptable threshold for FWER to be less than or equal to α.

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Before conducting a scientific study, a power analysis is performed to determine the sample size required to test an effect within allowable probabilities of Type I error (α) or Type II error (β). The power of a study is related to Type II error by 1-β. Most scientific studies set α=0.

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Study Design: Scoping review.

Objectives: To identify a practical and reproducible approach to organize Quality of Care Indicators (QoCI) in individuals with traumatic spinal cord injury (TSCI).

Methods: A comprehensive literature review was conducted in the Cochrane Central Register of Controlled Trials (CENTRAL) (Date: May 2018), MEDLINE (1946 to May 2018), and EMBASE (1974 to May 2018).

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Study Design: Retrospective, single institution, multisurgeon case control series.

Objective: To determine whether there are differences in reoperation rates or outcomes for patients undergoing 2-level posterolateral fusion (PLF) augmented by a transforaminal lumbar interbody fusion (TLIF) at only one of the levels or at both.

Methods: A total of 416 patients were identified who underwent 2-level PLF with a TLIF at either one of those levels (n = 183) or at both (n = 233) with greater than 1-year follow-up.

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Background: Surgical site infections (SSIs) represent a devastating complication after spine surgery. Many factors have been identified, but the influence of operating room (OR) size on infection rate has not been assessed.

Methods: Two thousand five hundred and twenty-three patients who underwent open lumbar spine fusion at a single institution between 2010 and 2016 were included.

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Purpose: Spinal Cord Society (SCS) and Spine Trauma Study Group (STSG) established a panel tasked with reviewing management and prognosis of acute traumatic cervical central cord syndrome (ATCCS) and recommend a consensus statement for its management.

Methods: A systematic review was performed according to the PRISMA 2009 guidelines. Delphi method was used to identify key research questions and achieve consensus.

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Spinal cord injury can be a life-altering trauma for patients and can be costly to patients and society alike. Generally recognized as biphasic, these injuries have both primary and secondary drivers. Although the primary insult is largely unavoidable, prevention of secondary injury mechanisms-and the resultant cascade-has been a target of substantial research.

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The management of thoracolumbar spine injuries in patients with multiple traumatic injuries is a challenge complicated by multiple competing medical and surgical demands. Safe and effective treatment of polytrauma patients with a thoracolumbar spine injury requires a multidisciplinary approach that involves surgical and critical care teams. The Thoracolumbar Injury Classification and Severity Score, which was developed to facilitate consistent surgical decision making in patients with a thoracolumbar spine injury, provides objective criteria for the classification and management of thoracolumbar spine injuries.

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Study Design: Analysis of a combined prospective dataset.

Objective: To evaluate the impact of preoperative body mass index (BMI) on surgical outcomes in degenerative cervical myelopathy (DCM).

Summary Of Background Data: Although elevated BMI has been shown to have a deleterious impact on outcomes after lumbar spine surgery, limited evidence is available regarding its impact in DCM.

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