Synopsis of recent research by authors named "Alex Rialdi"
- Alex Rialdi's recent research focuses on the identification of novel therapeutic targets for hepatocellular carcinoma (HCC) and hepatoblastoma, utilizing multi-kinase inhibitors and genomic profiling to improve precision medicine for these liver cancers.
- In his 2023 study, he discovered WNTinib as a selective multi-kinase inhibitor effective against β-catenin mutant HCC, demonstrating its potential in treating a high percentage of HCC cases that currently lack targeted therapies.
- Additionally, Rialdi's work has expanded to understanding how viral infections, particularly influenza, affect host cellular mechanisms, revealing global transcriptional defects that impact gene expression and immune responses.*