A myzozoan-specific protein is an essential membrane-anchoring component of the succinate dehydrogenase complex in parasites.

Succinate dehydrogenase (SDH) is a protein complex that functions in the tricarboxylic acid cycle and the electron transport chain of mitochondria. In most eukaryotes, SDH is highly conserved and comprises the following four subunits: SdhA and SdhB form the catalytic core of the complex, while SdhC and SdhD anchor the complex in the membrane. is an apicomplexan parasite that infects one-third of humans worldwide.

Experience, exposure, and attitudes regarding off-pump coronary artery bypass grafting techniques in US cardiothoracic surgical residents: Results of a survey.

Background: We sought to determine the current level of exposure to and interest in off-pump coronary artery bypass and beating heart surgery techniques regarding cardiothoracic surgical residents in the United States.

Methods: An email survey consisting of 6 questions was sent to all cardiothoracic surgery residents of approved cardiothoracic training programs in the United States. The survey was emailed using the Qualtrics XM cloud-based survey platform.

Evaluation of deep learning-based artificial intelligence techniques for breast cancer detection on mammograms: Results from a retrospective study using a BreastScreen Victoria dataset.

Introduction: This study aims to evaluate deep learning (DL)-based artificial intelligence (AI) techniques for detecting the presence of breast cancer on a digital mammogram image.

Methods: We evaluated several DL-based AI techniques that employ different approaches and backbone DL models and tested the effect on performance of using different data-processing strategies on a set of digital mammographic images with annotations of pathologically proven breast cancer.

Results: Our evaluation uses the area under curve (AUC) and accuracy (ACC) for performance measurement.

Risk-to-Benefit Relationship of Contralateral Prophylactic Mastectomy: The Argument for Bilateral Mastectomies with Immediate Reconstruction.

Background: The increasing trend of women with unilateral breast cancer to electively undergo contralateral prophylactic mastectomy in addition to treatment of the index breast has been controversial. The authors set out to better frame the risks and benefits of contralateral prophylactic mastectomy in the treatment of unilateral breast cancer by evaluating outcomes of a large, consecutive cohort of patients.

Methods: An institutional review board-approved review of a single-surgeon (N.

Three-dimensional echocardiography of mechanical circulatory support devices.

Two-dimensional echocardiography is a crucial component for assessing the position and function of mechanical circulatory support devices, but three-dimensional echocardiography provides additional information to aid in management and may improve accuracy in the assessment of these devices. In this article, we review the utility of three-dimensional echocardiography of various mechanical circulatory support devices.