Ocular surface microbiome in meibomian gland dysfunction.

Background: To investigate the ocular microbiome in meibomian gland dysfunction in Auckland, New Zealand.

Design: Prospective, cross-sectional, observational, university-based study.

Participants: Participants resident in New Zealand for ≥2 years (n = 157) were classified as normal (n = 66), mild (n = 41) or moderate-to-severe meibomian gland dysfunction (n = 50).

Efficacy and safety assessment of a novel ultraviolet C device for treating corneal bacterial infections.

Background: A prototype solid-state Ultraviolet-C (UVC) LED device may be useful in the treatment of corneal microbial infections, as UVC is commonly used for eradicating bacteria, fungi and viruses in other settings. This study assessed the efficacy of 265 nm UVC from this LED, on four different bacterial strains, and investigated the consequences of corresponding exposures on human corneal epithelial cells in vitro.

Methods: Agar plate lawns of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Streptococcus pyogenes were exposed to a 4.