Writing and Detecting Topological Charges in Exfoliated FeGeTe.

FeGeTe is a promising two-dimensional (2D) van der Waals (vdW) magnet for practical applications, given its magnetic properties. These include Curie temperatures above room temperature, and topological spin textures─TST (both merons and skyrmions), responsible for a pronounced anomalous Hall effect (AHE) and its topological counterpart (THE), which can be harvested for spintronics. Here, we show that both the AHE and THE can be amplified considerably by just adjusting the thickness of exfoliated FeGeTe, with THE becoming observable even in zero magnetic field due to a field-induced unbalance in topological charges.

Coexistence of Merons with Skyrmions in the Centrosymmetric Van Der Waals Ferromagnet Fe GeTe.

Fe GeTe is a centrosymmetric, layered van der Waals (vdW) ferromagnet that displays Curie temperatures T (270-330 K) that are within the useful range for spintronic applications. However, little is known about the interplay between its topological spin textures (e.g.

Trained Immunity in : Antibacterial Immunity Is Enhanced by Priming via Sugar Meal Supplemented With a Single Gut Symbiotic Bacterial Strain.

Mosquitoes have evolved an effective innate immune system. The mosquito gut accommodates various microbes, which play a crucial role in shaping the mosquito immune system during evolution. The resident bacteria in the gut microbiota play an essential role in priming basal immunity.

Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes.

In the CRISPR-Cas systems, Cas13a is an RNA-guided RNA nuclease specifically targeting single strand RNA. We developed a Cas13a mediated CRISPR interference tool to target mRNA for gene silencing in mosquitoes. A expressing plasmid was delivered to mosquitoes by intrathoracic injection, and transcripts were detectable at least 10 days post-delivery.

Widespread insecticide resistance in Aedes aegypti L. from New Mexico, U.S.A.

Background: Aedes aegypti mosquitoes are vectors of a variety of emerging viral pathogens, including yellow fever, dengue, chikungunya, and Zika virus. This species has established endemic populations in all cities across southern New Mexico sampled to date. Presently, control of Aedes-borne viruses relies on deployment of insecticides to suppress mosquito populations, but the evolution of insecticide resistance threatens the success of vector control programs.

Repair of injured spinal cord using biomaterial scaffolds and stem cells.

The loss of neurons and degeneration of axons after spinal cord injury result in the loss of sensory and motor functions. A bridging biomaterial construct that allows the axons to grow through has been investigated for the repair of injured spinal cord. Due to the hostility of the microenvironment in the lesion, multiple conditions need to be fulfilled to achieve improved functional recovery.