Publications by authors named "Alex Mezei"
Purpose: To assess the acceptability of integrated screening for cervical cancer and HIV in the community setting.
Methods: We developed surveys for patients and community health workers (CHWs) who participated in the Advances in Screening and Prevention in Reproductive Cancers (ASPIRE) Mayuge trial that compared self-collected human papillomavirus testing at home versus community health meetings in Mayuge district, Uganda. Quantitative data were summarized using descriptive statistics.
Background: Due to high burden of respiratory syncytial virus (RSV) in low- and middle-income countries (LMIC), international funding organizations have prioritized the development of RSV vaccines. Mathematical models of RSV will play an important role in assessing the relative value of these interventions. Our objectives were to provide an overview of the existing RSV modelling literature in LMIC and summarize available results on population-level effectiveness and cost-effectiveness.
View Article and Find Full Text PDFArticle Synopsis
- Cervical cancer is a major health issue for women in Uganda, but screening can help prevent it; a community-based self-collection method for HPV testing was proposed to make screening more accessible.
- The ASPIRE trial compared two screening methods: self-collected HPV testing facilitated by community health workers and clinic-based visual inspection, evaluating their effectiveness and cost.
- The results indicated that the HPV screen-and-treat strategy was the most effective and cost-effective option, significantly reducing cervical cancer risk while costing around $130 per year of life saved.
Background: The purpose of this study was to determine the socioeconomic implications of isolated tibial and femoral fractures caused by road traffic injuries in Uganda.
Methods: This prospective longitudinal study included adult patients who were admitted to Uganda's national referral hospital with an isolated tibial or femoral fracture. The primary outcome was the time to recovery following injury.
The incidence of cervical cancer in low- and middle-income countries (LMICs) is five times higher than that observed in high-income countries (HICs). This discrepancy is largely attributed to the implementation of cytology-based screening programmes in HICs. However, due to reduced health system infrastructure requirements, HPV testing (self- and provider-collected) and visual inspection with acetic acid (VIA) have been proposed as alternatives that may be better suited to LMICs.
View Article and Find Full Text PDFIntroduction: Traumatic injury is a growing public health concern globally, and is a major cause of death and disability worldwide. The purpose of this study was to quantify the socioeconomic impact of lower extremity fractures in Uganda.
Methods: All adult patients presenting acutely to Uganda's national referral hospital with a single long bone lower extremity fracture in October 2013 were recruited.