Complications, Reoperations, and Readmissions After Common Arthroscopic Sports Medicine Procedures of the Knee: An Analysis of the ABOS Part II Oral Examination Case List Database.

Background: Arthroscopic knee surgeries are among the most commonly performed orthopaedic surgeries, yet complications of these procedures are relatively understudied.

Purpose: To determine the rate of complications, reoperations, and readmissions for arthroscopic knee surgeries by procedure, patient characteristics, and physician fellowship training status using a large national database.

Study Design: Cross-sectional study; Level of evidence, 3.

Reverse Fragility Index Comparing Rates of Rerupture After Open Achilles Tendon Repair Versus Early Functional Rehabilitation: A Systematic Review of Randomized Controlled Trials.

Background: Despite similar published rates of rerupture among patients treated with early functional rehabilitation and open repair for acute Achilles tendon rupture, uncertainty still exists regarding the optimal treatment modality. The reverse fragility index (RFI) is a statistical tool that provides an objective measure of the study's neutrality by determining the number of events that need to change for a nonsignificant result to be significant.

Purpose: The purpose was to utilize the RFI to appraise the strength of neutrality of randomized controlled trials (RCTs) comparing the rerupture rates of acute Achilles tendon ruptures treated with open repair versus early functional rehabilitation.

Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer.

Pevonedistat (MLN4924), a selective inhibitor of the NEDD8-activating enzyme E1 regulatory subunit (NAE1), has demonstrated significant therapeutic potential in several malignancies. Although multiple mechanisms-of-action have been identified, how MLN4924 induces cell death and its potential as a combinatorial agent with standard-of-care (SoC) chemotherapy in colorectal cancer (CRC) remains largely undefined. In an effort to understand MLN4924-induced cell death in CRC, we identified p53 as an important mediator of the apoptotic response to MLN4924.

Evaluation of Knee Cartilage Diurnal, Activity, and BMI-Related Variations Using Quantitative T2 Mapping MRI and Fitbit Activity Tracking.

The aim of this study is to evaluate diurnal variation in knee cartilage 3 Tesla magnetic resonance imaging (MRI) T2 mapping relaxation times, as well as activity- and body mass index (BMI)-dependent variability, using quantitative analysis of T2 values from segmented regions of the weight-bearing articular surfaces of the medial and lateral femoral condyles and tibial plateaus. Ten healthy volunteers' daily activity (steps) were tracked with Fitbit pedometers. Sagittal MRI T2 maps were obtained in the morning and afternoon on days 2 and 3.

Interactive effects of insomnia symptoms and trauma exposure on PTSD: Examination of symptom specificity.

Objective: Although symptoms of posttraumatic stress disorder (PTSD) are common following exposure to a traumatic event, most people who experience trauma do not develop PTSD. Thus, the identification of risk factors that may interact with trauma exposure to confer vulnerability for the development of PTSD may highlight important targets for prevention and treatment. Recent research suggests that sleep disturbance amplifies the effect of maladaptive emotional processes on PTSD symptom severity.

Saccades and smooth pursuit eye movements trigger equivalent gaze-cued orienting effects.

Research has established that a perceived eye gaze produces a concomitant shift in a viewer's spatial attention in the direction of that gaze. The two experiments reported here investigate the extent to which the nature of the eye movement made by the gazer contributes to this orienting effect. On each trial in these experiments, participants were asked to make a speeded response to a target that could appear in a location toward which a centrally presented face had just gazed (a cued target) or in a location that was not the recipient of a gaze (an uncued target).

Arthroscopic Excision of a Symptomatic Meso-acromiale.

The surgical technique for the management of a symptomatic os acromiale remains unclear. Several operative techniques have been described including open excision, open reduction-internal fixation (ORIF), arthroscopic acromioplasty or subacromial decompression, and arthroscopic excision. There are 4 types of os acromiale, with the meso-acromion being the most common and difficult to treat.

Holistic face processing can inhibit recognition of forensic facial composites.

Facial composite systems help eyewitnesses to show the appearance of criminals. However, likenesses created by unfamiliar witnesses will not be completely accurate, and people familiar with the target can find them difficult to identify. Faces are processed holistically; we explore whether this impairs identification of inaccurate composite images and whether recognition can be improved.

Developmentally distinct gaze processing systems: luminance versus geometric cues.

Two experiments examined how the different cues to gaze direction contribute to children's abilities to follow and make explicit judgements about gaze. In each study participants were shown blurred images of faces containing only luminance cues to gaze direction, line-drawn images containing only fine-grained detail supporting a geometric analysis of gaze direction, and unmanipulated images. In Experiment 1a, 2- and 3-year olds showed gaze-cued orienting of attention in response to unmanipulated and blurred faces, but not line-drawn faces.

Configural and featural information in facial-composite images.

Eyewitnesses are often invited to construct a facial composite, an image created of the person they saw commit a crime that is used by law enforcement to locate criminal suspects. In the current paper, the effectiveness of composite images was investigated from traditional feature systems (E-FIT and PRO-fit), where participants (face constructors) selected individual features to build the face, and a more recent holistic system (EvoFIT), where they 'evolved' a composite by repeatedly selecting from arrays of complete faces. Further participants attempted to name these composites when seen as an unaltered image, or when blurred, rotated, linearly stretched or converted to a photographic negative.

Whole-face procedures for recovering facial images from memory.

Research has indicated that traditional methods for accessing facial memories usually yield unidentifiable images. Recent research, however, has made important improvements in this area to the witness interview, method used for constructing the face and recognition of finished composites. Here, we investigated whether three of these improvements would produce even-more recognisable images when used in conjunction with each other.

Recovering faces from memory: the distracting influence of external facial features.

Recognition memory for unfamiliar faces is facilitated when contextual cues (e.g., head pose, background environment, hair and clothing) are consistent between study and test.

The relative importance of external and internal features of facial composites.

Three experiments are reported that compare the quality of external with internal regions within a set of facial composites using two matching-type tasks. Composites are constructed with the aim of triggering recognition from people familiar with the targets, and past research suggests internal face features dominate representations of familiar faces in memory. However the experiments reported here show that the internal regions of composites are very poorly matched against the faces they purport to represent, while external feature regions alone were matched almost as well as complete composites.