Publications by authors named "Alex Legocki"

Background/aims: Handheld swept-source optical coherence tomography (SS-OCT) was previously used to measure foveal maturity through semiautomated methods in awake premature infants. This study assesses the relationship between foveal maturity and retinopathy of prematurity (ROP) severity.

Methods: This is a prospective, observational study using handheld SS-OCT imaging of premature infants undergoing ROP screening.

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Article Synopsis
  • The study investigates dome-shaped macula (DSM) in preterm and full-term infants using advanced optical imaging technology, highlighting increased occurrence in preterm infants.
  • Out of 217 imaging sessions, DSM was found in 40% of preterm infants compared to 14% of full-term infants, showing a significant difference in diagnosis timing and dome characteristics.
  • The results suggest that while DSM is common in infants and typically round in shape, it isn't linked to macular fluid presence, indicating unique differences from DSM in older children and adults.
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Purpose: We explored the associations between socioeconomic status, as evaluated by the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry Social Vulnerability Index (SVI), and characteristics of open globe injury (OGI) in a Level I trauma center during the COVID-19 pandemic.

Methods: Retrospective review of electronic medical records of patients who underwent OGI evaluation and repair at Harborview Medical Center between March/2017 and March/2021. Demographic data and patient characteristics were recorded.

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Purpose: To directly compare margin-reflex distance 1, margin-reflex distance 2, and palpebral fissure in the upright versus supine positions in nonsurgical patients.

Methods: A total of 43 patients (31 female, 12 male, and age range 26-96) were enrolled. Photos were taken in the clinic in the upright and supine position with a ruler placed vertically in the same plane as the eyelid, and the above computer-analyzed measurements were obtained.

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Purpose: The purpose of this study was to create multivariate models predicting early referral-warranted retinopathy of prematurity (ROP) using non-contact handheld spectral-domain optical coherence tomography (OCT) and demographic data.

Methods: Between July 2015 and February 2018, infants ≤1500 grams birth weight or ≤30 weeks gestational age from 2 academic neonatal intensive care units were eligible for this study. Infants were excluded if they were too unstable to participate in ophthalmologic examination (2), had inadequate image quality (20), or received prior ROP treatment (2).

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Article Synopsis
  • * The effectiveness of the removal procedure depends on the type of eye structure affected and the specific attributes of the hook.
  • * A new surgical technique called the clamp and retract technique was successfully used for the first time to remove a fishhook from the eyelid of an eight-year-old boy, due to challenges faced with traditional methods.
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Purpose: To develop a semi-automated method of measuring foveal maturity using investigational handheld swept source-optical coherence tomography (SS-OCT).

Methods: In this prospective, observational study, full-term newborns and preterm infants undergoing routine retinopathy of prematurity screening were imaged. Semi-automated analysis measured foveal angle and chorioretinal thicknesses at the central fovea and average two-sided parafovea by three-grader consensus, correlating with OCT features and demographics.

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Purpose: To compare vitreous opacity density in infants born at term and in infants born prematurely using an investigational handheld swept-source optical coherence tomography (SS-OCT).

Methods: Infants born at term underwent imaging once between 12 and 48 hours after birth; infants born prematurely were imaged at each routine retinopathy of prematurity (ROP) examination. Three masked, trained graders analyzed images.

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Article Synopsis
  • The study aimed to validate a custom algorithm that automatically identifies and measures inflammatory lesions in the choriocapillaris using en face SS-OCTA images from patients with posterior uveitis.
  • Twenty eyes from 14 patients were analyzed, with the algorithm's findings compared to those of two human graders for accuracy and reliability.
  • Results showed the algorithm had excellent agreement with human assessments, especially in measuring lesion areas, and was more reliable than humans for repeated measurements, indicating its potential as a clinical tool for monitoring disease activity.
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Purpose: To describe dome-shaped macula and associated clinical findings in premature infants.

Methods: This prospective, observational cohort study included a consecutive sample of premature infants screened for retinopathy of prematurity (ROP) with 9-month follow-up. Handheld spectral domain optical coherence tomography (SD-OCT) was performed at the time of ROP screening.

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Purpose: To describe normative values for choroidal thickness in newborns and characterize their relationship to vitreoretinal features.

Methods: Term newborns underwent awake, handheld swept-source optical coherence tomography (SS-OCT) in this prospective cohort study. An automated segmentation algorithm followed by manual adjustments measured choroidal thickness at the fovea and five perifoveal locations.

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Purpose: To compare retinal vascular parameters acquired by handheld swept-source optical coherence tomography angiography (SS-OCTA) between nonsedated preterm and full-term infants.

Methods: Preterm and full-term infants at the University of Washington Medical Center were enrolled. Retinal angiograms (nominal size ∼7 × 7 mm) were obtained at each routine retinopathy of prematurity (ROP) screening session for preterms and once during the first 72 hours of life for full-terms.

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Purpose: To evaluate the association between retinopathy of prematurity (ROP) and vitreous findings in premature infants detected by handheld spectral-domain (SD) OCT.

Design: Prospective, observational cohort study.

Participants: Consecutive sample of 92 premature infants requiring ROP screening at 2 academic neonatal intensive care units between July 2015 and March 2018.

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Background: Retinopathy of prematurity (ROP) can lead to retinal detachment and severe vision loss and is a common cause of childhood blindness. Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can be used to detect potential abnormalities in the microvasculature in this population. The objective of this study is to assess the feasibility of a newly developed handheld swept source OCT (SS-OCT) device to successfully acquire structural vitreoretinal and retinal microvascular images in awake premature infants.

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Orbital reconstruction following oncologic midface resection is uniquely challenging, and makes critical contributions to patient aesthetics, function, and identity. Approach is largely dependent on surgeon and patient preferences, and there exists no consensus on defect characterization. The goal of the study is to provide a mental framework for the reconstructive oncologic surgeon to use as a foundation during his or her approach to the orbit.

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Purpose: To evaluate whether patient demographics and surgical metrics varied among differently trained surgeons performing blepharoplasty.

Methods: The Statewide Planning and Research Cooperative System database was used to identify patients who underwent blepharoplasty in New York State. Surgeons were grouped based on residency training as listed in the New York State Physician Profile.

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Importance: A protocol for creating exceptionally low-cost 3-dimensional (3-D) maxillofacial skeletal models does not require proficiency with computer software or intensive labor. Small and less affluent centers can produce models with little loss in accuracy and clinical utility.

Objectives: To highlight the feasibility and methods of introducing in-house, entry-level additive manufacturing (3-D printing) technology to otolaryngologic craniofacial reconstruction and to describe its clinical applications and limitations, including a comparison with available vendor models.

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Background And Objective: To describe morphology and vascular layer thickness of the choroid in eyes with neovascular age-related macular degeneration (AMD) using spectral-domain optical coherence tomography (SD-OCT).

Patients And Methods: Cross-sectional, retrospective analysis of 15 eyes with neovascular AMD and 11 healthy age-matched eyes that underwent single horizontal, high-definition raster line imaging using high-definition SD-OCT. Two independent graders assessed choroid morphology and measured the thickness of individual vascular layers of the choroid beneath the fovea.

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Objectives: To determine the most common mechanisms of traumatic nasal deformity referred to pediatric otolaryngology. To examine the efficacy of closed reduction of nasal fractures in children and adolescents based on the parents' and surgeons' ratings of post-reduction nasal symmetry.

Methods: Case series and chart review within an urban, tertiary pediatric otolaryngology practice.

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