Synopsis of recent research by authors named "Alex J Eddins"
- Alex J Eddins' recent research focuses on advanced techniques for protein bioconjugation, single-cell proteomics, and imaging, emphasizing the development of innovative methodologies such as bioorthogonal ligations, thermal inkjet systems, and new fluorescent amino acids for enhanced label-free and quantitative analysis of proteins.
- His studies demonstrate the successful application of a thermal inkjet platform for single-cell proteomics, achieving the identification of large numbers of proteins (up to 1,300) with a reproducible and robust workflow suitable for various lab formats.
- Eddins also explores the optimization of labeling strategies for cell surface proteins using non-canonical amino acids and tetrazine click chemistry, providing crucial protocols that facilitate the study of ion channel dynamics and receptor expression in neuronal cells without disrupting their function.
