Scapholunate ligament injuries: an instructional review for the FRCS examination.

An instructional review of the anatomy, investigation, and management of scapholunate ligament injuries. Aimed at the knowledge level required for the trauma and orthopaedic FRCS examination.

Profiling of myristoylation in reveals an -myristoylated protein important for host cell penetration.

-myristoylation is a ubiquitous class of protein lipidation across eukaryotes and -myristoyl transferase (NMT) has been proposed as an attractive drug target in several pathogens. Myristoylation often primes for subsequent palmitoylation and stable membrane attachment, however, growing evidence suggests additional regulatory roles for myristoylation on proteins. Here we describe the myristoylated proteome of using chemoproteomic methods and show that a small-molecule NMT inhibitor developed against related .

Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of .

contains a limited subset of actin binding proteins. Here we show that the putative actin regulator cyclase-associated protein (CAP) is present in two different isoforms and its deletion leads to significant defects in some but not all actin dependent processes. We observe defects in cell-cell communication, daughter cell orientation and the juxtanuclear accumulation of actin, but only modest defects in synchronicity of division and no defect in the replication of the apicoplast.

Analyzing Moment Arm Profiles in a Full-Muscle Rat Hindlimb Model.

Understanding the kinematics of a hindlimb model is a fundamental aspect of modeling coordinated locomotion. This work describes the development process of a rat hindlimb model that contains a complete muscular system and incorporates physiological walking data to examine realistic muscle movements during a step cycle. Moment arm profiles for selected muscles are analyzed and presented as the first steps to calculating torque generation at hindlimb joints.

Efficacy of an 8-Week Concurrent Strength and Endurance Training program on Hand Cycling Performance.

Nevin, JP, Smith, P, Waldron, M, Patterson, S, Price, M, Hunt, A, and Blagrove, R. Efficacy of an 8-week concurrent strength and endurance training program on hand cycling performance. J Strength Cond Res 32(7): 1861-1868, 2018-The aim of this study was to investigate the effects of an 8-week concurrent strength and endurance training program in comparison with endurance training only on several key determinants of hand cycling performance.

The potential for dispersant use as a maritime oil spill response measure in German waters.

In case of an oil spill, dispersant application represents a response option, which enhances the natural dispersion of oil and thus reduces coating of seabirds and coastal areas. However, as oil is transferred to the water phase, a trade-off of potential harmful effects shifted to other compartments must be performed. This paper summarizes the results of a workshop on the current knowledge on risks and benefits of the use of dispersants with respect to specific conditions encountered at the German sea areas.