Publications by authors named "Alex Hung"

Background & Aims: Effective treatment for anterior drooling in children with neurological disorders can lead to improved social interactions, reduced physical complications such as perioral infections, and enhanced quality of life for both patients and their parents. Elastic therapeutic taping (ETT) has emerged a novel intervention for drooling, but its evidence was limited. This study systematically reviewed the effectiveness of ETT on reducing anterior drooling in children with neurological disorders.

View Article and Find Full Text PDF

Current deep learning-based models typically analyze medical images in either 2D or 3D albeit disregarding volumetric information or suffering sub-optimal performance due to the anisotropic resolution of MR data. Furthermore, providing an accurate uncertainty estimation is beneficial to clinicians, as it indicates how confident a model is about its prediction. We propose a novel 2.

View Article and Find Full Text PDF

Medical images often require rescaling to various spatial resolutions to ensure interpretations at different levels. Conventional deep learning-based image super-resolution (SR) enhances the fixed-scale resolution. Implicit neural representation (INR) is a promising way of achieving arbitrary-scale image SR.

View Article and Find Full Text PDF

Diffusion models have achieved impressive performance on various image generation tasks, including image super-resolution. Despite their impressive performance, diffusion models suffer from high computational costs due to the large number of denoising steps. In this paper, we proposed a novel accelerated diffusion model, termed Partial Diffusion Models (PDMs), for magnetic resonance imaging (MRI) super-resolution.

View Article and Find Full Text PDF

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) measures microvascular perfusion by capturing the temporal changes of an MRI contrast agent in a target tissue, and it provides valuable information for the diagnosis and prognosis of a wide range of tumors. Quantitative DCE-MRI analysis commonly relies on the nonlinear least square (NLLS) fitting of a pharmacokinetic (PK) model to concentration curves. However, the voxel-wise application of such nonlinear curve fitting is highly time-consuming.

View Article and Find Full Text PDF

Multi-parametric MRI (mpMRI) is widely used for prostate cancer (PCa) diagnosis. Deep learning models show good performance in detecting PCa on mpMRI, but domain-specific PCa-related anatomical information is sometimes overlooked and not fully explored even by state-of-the-art deep learning models, causing potential suboptimal performances in PCa detection. Symmetric-related anatomical information is commonly used when distinguishing PCa lesions from other visually similar but benign prostate tissue.

View Article and Find Full Text PDF

Conditional image generation plays a vital role in medical image analysis as it is effective in tasks such as super-resolution, denoising, and inpainting, among others. Diffusion models have been shown to perform at a state-of-the-art level in natural image generation, but they have not been thoroughly studied in medical image generation with specific conditions. Moreover, current medical image generation models have their own problems, limiting their usage in various medical image generation tasks.

View Article and Find Full Text PDF

This study evaluated the effects of heat stress (HS) and dietary nano chromium picolinate (nCrPic) on metabolic responses of sheep to an intravenous glucose tolerance test (IVGTT), an intravenous insulin tolerance test (ITT) and an intramuscular adrenocorticotropin hormone (ACTH) challenge in sheep. Thirty-six sheep housed in metabolic cages were randomly allocated within 3 dietary groups (0, 400 and 800 μg/kg supplemental nCrPic) to either thermoneutral (22 °C) or cyclic HS (22 to 40 °C) conditions for 3 wk. Basal plasma glucose tended to be increased during HS ( = 0.

View Article and Find Full Text PDF

Prostate cancer is the second leading cause of cancer death among men in the United States. The diagnosis of prostate MRI often relies on accurate prostate zonal segmentation. However, state-of-the-art automatic segmentation methods often fail to produce well-contained volumetric segmentation of the prostate zones since certain slices of prostate MRI, such as base and apex slices, are harder to segment than other slices.

View Article and Find Full Text PDF

We propose a weakly- and semisupervised, probabilistic needle-and-reverberation-artifact segmentation algorithm to separate the desired tissue-based pixel values from the superimposed artifacts. Our method models the intensity decay of artifact intensities and is designed to minimize the human labeling error. Ultrasound image quality has continually been improving.

View Article and Find Full Text PDF

Purpose: Ultrasound compounding is to combine sonographic information captured from different angles and produce a single image. It is important for multi-view reconstruction, but as of yet there is no consensus on best practices for compounding. Current popular methods inevitably suppress or altogether leave out bright or dark regions that are useful and potentially introduce new artifacts.

View Article and Find Full Text PDF

Two studies were conducted to evaluate the effect of nano chromium picolinate (nCrPic) during heat stress (HS) in sheep. In the initial study, 36 Merino × Poll cross-bred sheep were individually penned and allocated to 3 dietary treatments (0, 400 and 800 μg/kg nCrPic) for 8 wk. Body composition was determined at the beginning and end of the experiment using dual energy X-ray absorptiometry.

View Article and Find Full Text PDF

Ischaemic colitis (IC) is a common condition with rising incidence, and in severe cases a high mortality rate. Its presentation, severity and disease behaviour can vary widely, and there exists significant heterogeneity in treatment strategies and resultant outcomes. In this article we explore practical challenges in the management of IC, and where available make evidence-based recommendations for its management based on a comprehensive review of available literature.

View Article and Find Full Text PDF

The aim of this study was to investigate the effects of sex and dietary lecithin on growth performance, meat quality, muscle collagen content and gene expression of key genes involved in collagen synthesis in finisher pigs. A total of 256 pigs (Large White × Landrace) were allotted to a 2 × 2 factorial arrangement involving sex (gilt or immunocastrated [IC] male) and dietary treatment (0 or 5 g/kg of dietary lecithin). All diets were formulated to contain 4.

View Article and Find Full Text PDF

We present and analyze two pathways to produce commercial optical-fiber patch cords with stable long-term transmission in the ultraviolet (UV) at powers up to ~ 200 mW, and typical bulk transmission between 66-75 %. Commercial fiber patch cords in the UV are of great interest across a wide variety of scientific applications ranging from biology to metrology, and the lack of availability has yet to be suitably addressed. We provide a guide to producing such solarization-resistant, hydrogen-passivated, polarization-maintaining, connectorized and jacketed optical fibers compatible with demanding scientific and industrial applications.

View Article and Find Full Text PDF
Article Synopsis
  • This study examined how dietary lecithin affects gene expression related to collagen production and breakdown in skeletal muscle of finisher gilts.
  • Gilts were fed diets with varying levels of soybean lecithin, and results showed that lecithin reduced the expression of key collagen precursor genes (COL1A1 and COL3A1) and a related enzyme (P4H), suggesting lowered collagen synthesis.
  • Despite these reductions, the study indicates that further research is needed to measure actual muscle collagen content and properties to fully understand lecithin's effects on muscle tissue.
View Article and Find Full Text PDF

Chromium (Cr) is an essential mineral element and has been used in pig diets to improve growth performance, insulin sensitivity, immune response and carcase traits and to reduce heat or other stress responses. The aims of thiss study were to determine the impact of nano-sized chromium tripicolinate (nCrPic) on growth performance, feed efficiency and carcase characteristics of finisher gilts during the summer period. A total of 60 finisher Large White x Landrace gilts were stratified on initial weight and then within strata randomly allocated into two treatment groups in three replicates during mid-summer for 28 days.

View Article and Find Full Text PDF

Background: Magnetic resonance diffusion-weighted imaging (DWI) has been widely used clinically in imaging diagnosis of intracranial disorders. The purpose of current study was to present a quantitative method of direct measuring the DWI signal intensity of brain gliomas on the monitors of hospital picture archiving and communicating system (PACS) for grading gliomas.

Methods: This study recruited 135 patients with treatment-naïve brain gliomas.

View Article and Find Full Text PDF

Objectives: To determine the clinical and radiological features of severe acute respiratory syndrome (SARS) and to evaluate the accuracy of the World Health Organization's guidelines on defining cases of SARS.

Design: Prospective observational study.

Setting: A newly set up SARS screening clinic in the emergency department of a university hospital in Hong Kong's New Territories.

View Article and Find Full Text PDF