Publications by authors named "Alex Hilbert"

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutation in the X-linked gene, encoding methyl-CpG-binding protein 2. We have created a mouse model ( A140V "knock-in" mutant) expressing the recurrent human A140V mutation linked to an X-linked mental retardation/Rett syndrome phenotype. Morphological analyses focused on quantifying soma and nucleus size were performed on primary hippocampus and cerebellum granule neuron (CGN) cultures from mutant ( ) and wild type ( ) male mice.

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