Publications by authors named "Alex Gan"

Article Synopsis
  • A 23-year-old South Asian man developed a darkly pigmented papule on his scalp, which grew within a pre-existing warty plaque present since birth.
  • The papule showed characteristics indicative of basal cell carcinoma (BCC) when examined and biopsied, confirming it developed from a sebaceous naevus.
  • Sebaceous naevi are benign skin lesions that can develop into malignancies like BCC in a small percentage of cases, especially in adults.
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How countries, particularly low- and middle-income economies, should pay the coronavirus disease 2019 (COVID-19) vaccine is an important and understudied issue. We undertook an online survey to measure the willingness-to-pay (WTP) for a COVID-19 vaccine and its determinants in Indonesia. The WTP was assessed using a simple dichotomous contingent valuation approach and a linear regression model was used to assess its associated determinants.

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Objectives: The aim of this study was to determine the level of coronavirus disease 2019 (COVID-19) risk perceptions in Indonesia and characterize predictors of perceptions.

Methods: An online cross-sectional study was conducted. A questionnaire assessed perceived risk and collected independent variables, including sociodemographic data.

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Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population in Indonesia. A cross-sectional online survey was conducted between March 25 and April 6, 2020.

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Article Synopsis
  • Ovarian cancers with BRCA mutations utilize the PARP-dependent repair pathway, leading to better survival and chemotherapy response, which can be enhanced with PARP inhibitors.
  • High expression of PARP1, regardless of BRCA status, is linked to poorer disease outcomes, suggesting it may serve as a biomarker for identifying patients likely to respond well to PARP inhibitors.
  • Analysis of 174 patients showed that elevated PARP1 correlates with decreased overall and progression-free survival, with PARP1 identified as an independent prognostic factor.
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