Publications by authors named "Alex G Contreras"
JAMA Neurol
September 2023
Article Synopsis
- The study investigates how sex and race influence the relationship between apolipoprotein E (APOE) alleles (ε4 and ε2) and cognitive function in Alzheimer’s disease (AD) across different populations.
- Using data from four cohorts of older adults (60+ years) who self-identified as either non-Hispanic White or non-Hispanic Black, researchers analyzed cognitive outcomes related to memory and executive function.
- Findings suggest significant differences in how APOE ε4 impacts cognitive scores based on sex, with the interactions varying by race, indicating that genetic factors influencing cognition in AD are complex and multifaceted.
