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Publications by authors named "Alex Castonguay"

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Efficacy, tolerability, and endometrial safety of ospemifene compared with current therapies for the treatment of vulvovaginal atrophy: a systematic literature review and network meta-analysis.
James A Simon Alex Ferenczy Denise Black Alex Castonguay Catherine Royer

Menopause

August 2023

Importance: Ospemifene is a novel selective estrogen receptor modulator developed for the treatment of moderate to severe postmenopausal vulvovaginal atrophy (VVA).

Objective: The aim of the study is to perform a systematic literature review (SLR) and network meta-analysis (NMA) to assess the efficacy and safety of ospemifene compared with other therapies used in the treatment of VVA in North America and Europe.

Evidence Review: Electronic database searches were conducted in November 2021 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

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Synopsis of recent research by authors named "Alex Castonguay"

  • - Alex Castonguay's research primarily focuses on the treatment of postmenopausal vulvovaginal atrophy (VVA) and evaluates the effectiveness of the novel drug ospemifene compared to existing therapies.
  • - His recent publication presents a systematic literature review and network meta-analysis demonstrating ospemifene's efficacy, tolerability, and endometrial safety, highlighting its potential benefits for women's health.
  • - The comprehensive study underscores the importance of evidence-based approaches in assessing new treatments and offers a comparative analysis that may influence clinical practices in North America and Europe.

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