Publications by authors named "Alex Bonai"
Mycotoxin Res
December 2009
Article Synopsis
- Lymphocytes from healthy humans and pigs were tested for their viability after being exposed to the mycotoxins fumonisin B1 (FB1) and ochratoxin A (OTA), known for their immunosuppressive and carcinogenic properties.
- The study aimed to explore the effectiveness of pig lymphocytes in the MTT cytotoxicity test as a more accessible alternative to human lymphocytes and assess the toxic effects of the mycotoxins both individually and in combination.
- Results indicated that exposure to these toxins led to decreased lymphocyte viability over time, with FB1 being less toxic than OTA, and a synergistic effect was observed when both toxins were combined, particularly affecting pig lymphocytes more severely.
