Acquired reading impairment following brain injury.

This large-scale patient study investigated the rate, unique signatures associated with acquired reading impairments, its neurocognitive correlates, and long-term outcome in 731 acute stroke patients using the sentence and non-word reading subtests of Birmingham Cognitive Screen (BCoS). The objectives for the study were to explore the (i) potentially different error patterns among adult patients, (ii) associative relationship between the different subclasses of reading impairment and performance in other cognitive domains, and (iii) recovery rates in patients nine months post-lesion compared with their initial performance. The study revealed distinctive reading impairment profiles in patients with left hemisphere (LH) and right hemisphere (RH) lesions.

Cross-modal information transfer and the effect of concurrent task-load.

People's everyday lives offer plenty of situations where complex processing of information takes place, in which information needs to transfer across modalities to achieve a behavioral goal. The study examined the differential effects on object detection by a visual, verbal, or auditory cue held in working memory (WM), and the role of concurrent cognitive task-load on the final detection of that cue. Three experiments, all using same stimuli set but in different modalities, subjects held in memory a representation of a novel cue for a speeded detection in a search display at the end of each trial.

Systematic assessment of apraxia and functional predictions from the Birmingham Cognitive Screen.

Objective: The validity and functional predictive values of the apraxia tests in the Birmingham Cognitive Screen (BCoS) were evaluated. BCoS was developed to identify patients with different forms of praxic deficit using procedures designed to be inclusive for patients with aphasia and/or spatial neglect.

Method: Observational studies were conducted from a university neuropsychological assessment centre and from acute and rehabilitation stroke care hospitals throughout an English region.

Separating top-down and bottom-up cueing of attention from response inhibition in utilization behavior.

A single case study of a patient (FK) with utilization disorder following bilateral damage to medial frontal and anterior temporal cortices is reported. FK had to localize a search target following presentation of an earlier verbal or visual cue. Search was strongly affected by semantic/visual associations between the cue and search items.

Working memory and target-related distractor effects on visual search.

We examined two forms of top-down effects on visual selection: (1) information held in working memory (WM) and (2) the semantic relations between targets and distractors. We found that items held in WM affected search for a different target. This WM-based interference effect generalized across different exemplars, even though participants could remember the specific exemplar on the trial.

Working memory enhances visual perception: evidence from signal detection analysis.

We show that perceptual sensitivity to visual stimuli can be modulated by matches between the contents of working memory (WM) and stimuli in the visual field. Observers were presented with an object cue (to hold in WM or to merely attend) and subsequently had to identify a brief target presented within a colored shape. The cue could be re-presented in the display, where it surrounded either the target (on valid trials) or a distractor (on invalid trials).

Constraints on task-based control of behaviour following frontal lobe damage: a single-case study.

What factors determine stimulus-driven responses in patients with utilization behaviour? We examined this question by assessing the influence of an irrelevant cue on visual search in a patient showing evidence of utilization behaviour (F.K.), following bilateral damage to the medial frontal and temporal lobes.