Publications by authors named "Alessio Zavaroni"
Int J Mol Sci
October 2024
Article Synopsis
- Research in metallodrugs is growing, but a key challenge is their low water solubility; to address this, new ligands (NaHL) were synthesized that show improved solubility.
- The ligands' ability to bind with Cu(II) and Zn(II) ions was studied, leading to the isolation of metal complexes and the determination of their structure and stability.
- Initial tests on cell lines indicated that the Cu(II) complexes had significant cytotoxic effects, achieving approximately 40-45% growth inhibition, while Zn(II) complexes showed no toxic effects in normal cells.
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