Publications by authors named "Alessio Lusci Gemignani"
Int J Lab Hematol
September 2024
Article Synopsis
- Epigenetics plays a significant role in various cancers, including diffuse large B-cell lymphoma (DLBCL), where the expression of genes BMI1, EZH2, and USP22 is being studied for their impact on prognosis.
- A multiplex digital droplet PCR (ddPCR) method was developed to measure the levels of these genes in RNA from tissue samples, showing high specificity and repeatability.
- Results indicated that elevated levels of BMI1 and USP22 correlate with worse progression-free survival (PFS) and overall survival (OS) in high-risk DLBCL patients, suggesting these genes could be potential targets for new treatments.
